Frequency Therapeutics — Hearing Loss Regeneration

[KMc24]

OK,and what did your ENT mention with that?did she say something more precise? Does she know more?

She was aware of the mixed results from the trials conducted. She recently attended a conference on tinnitus.

 

[Chestnut94]

She doesnt know anything more than the people on this thread. They treat people with what is available now, not something that might be available in the future.

I agree, but if an 'outsider' ENT is aware of this specific company, then that is somewhat comforting for me.

 

[lapidus]

She was aware of the mixed results from the trials conducted.

Wasn't that what she said about Lenire? This is about FX-322.

 

[KMc24]

Wasn't that what she said about Lenire? This is about FX-322.

Correct. That's what she said about Lenire. As far as regeneration she didn't say when she thought it would be made available to the public.

 

[RB2014]

I agree, but if an 'outsider' ENT is aware of this specific company, then that is somewhat comforting for me.

Every time I see my audiologist I fill her in on what is going on. They barely keep up with it. They spend most of their time trying to help people with what is available on the market now. It's also not something they can sell to you. Hearing aids and cochlear implants though...

 

[KMc24]

Every time I see my audiologist I fill her in on what is going on. They barely keep up with it. They spend most of their time trying to help people with what is available on the market now. It's also not something they can sell to you. Hearing aids and cochlear implants though...

I was pleasantly surprised by my ENT's response and her knowledge about the research being done on tinnitus. She had just attended a conference where they discussed the latest research. On a positive note based on the changes to my tinnitus she believes that I am healing to a certain degree.

 

[JoNo78]

Well... I hope that the FX-322 as well as the development of the European Audion REGAIN project will be successful! And that the drug(s) will be on the market as soon as possible!

 

[Flamingo1]

Well... I hope that the FX-322 as well as the development of the European Audion REGAIN project will be successful! And that the drug(s) will be on the market as soon as possible!

Check back in a year or two.

 

[Lucifer]

So will this drug cure tinnitus?

 

[Kaleo]

Maybe, we don't really know yet but if your tinnitus is noise induced they think it may help.

Been lurking on the forums but I have two questions which I think haven't been addressed, maybe because we don't know the answer:

1. Does anyone know when this big tinnitus conference is where Frequency Therapeutics will supposedly release their results?

2. Does anyone know the difference between Frequency Therapeutics drug and Audion Therapeutics REGAIN project? Do they both aim to reactivate progenitor cells?

Thanks.

 

[Lucifer]

Maybe, we don't really know yet but if your tinnitus is noise induced they think it may help.

Been lurking on the forums but I have two questions which I think haven't been addressed, maybe because we don't know the answer:

1. Does anyone know when this big tinnitus conference is where Frequency Therapeutics will supposedly release their results?

2. Does anyone know the difference between Frequency Therapeutics drug and Audion Therapeutics REGAIN project? Do they both aim to reactivate progenitor cells?

Thanks.

Definitely a good question. Do you guys also believe that if there was a cure for tinnitus, would it also help cure hyperacusis as well?

 

[JohnAdams]

So will this drug cure tinnitus?

Maybe not cure, but improve.

 

[JohnAdams]

Definitely a good question. Do you guys also believe that if there was a cure for tinnitus, would it also help cure hyperacusis as well?

Yes.

 

[JoNo78]

https://www.cicada.org.au/index.php...itor-cell-activation-study-to-restore-hearing

https://www.openaccessgovernment.org/tinnitus-developing-effective-treatments/60579/

 

[JohnAdams]

https://www.cicada.org.au/index.php...itor-cell-activation-study-to-restore-hearing

https://www.openaccessgovernment.org/tinnitus-developing-effective-treatments/60579/

Lol cicada?

 

[JoNo78]

Lol cicada?

Why lol?

 

[JohnAdams]

Why lol?

Because tinnitus sounds like a cicada sometimes.

 

[KMc24]

Because tinnitus sounds like a cicada sometimes.

When my tinnitus spikes it sounds like a cicada. Terrible sound indeed.

 

[Lucifer]

@JohnAdams

Do you know of other companies that are currently doing clinical trials to cure tinnitus?

The only ones I know that are currently doing trials are Frequency Therapeutics, Decibel Therapeutics and Sensorion?

 

[JoNo78]

I hope that the tinnitus will reduce when the hearing is restored, so let's look forward and hope that the clinical trials will be successful!

There is also a project running in the EU (REGAIN).

 

[SergioN]

And Otonomy products, right?

 

[JohnAdams]

Do you know of other companies that are currently doing clinical trials to cure tinnitus?

Otonomy, but I don't know if they have initiated their trials as of yet. There could be more.

 

[Lucifer]

Otonomy, but I don't know if they have initiated their trials as of yet. There could be more.

Just looked at their website. When they state they are starting Phase 1/2, does that mean Phase 1 or Phase 1.5?

 

[JohnAdams]

Just looked at their website. When they state they are starting Phase 1/2, does that mean Phase 1 or Phase 1.5?

I don't think there is a phase 1.5.

Each phase is designed to meet certain endpoints and there could be multiple trials for each phase. Like 1, 1/2, 1/3, 2, 2/2, 2/3, 2/4 etc.

Like how there's 50 versions of Street Fighter 2.

 

[Lucifer]

I don't think there is a phase 1.5.

Each phase is designed to meet certain endpoints and there could be multiple trials for each phase. Like 1, 1/2, 1/3, 2, 2/2, 2/3, 2/4 etc.

Like how there's 50 versions of Street Fighter 2.

Out of Frequency Therapeutics, Decibel Therapeutics, Sensorion and Otonomy which one do you believe will actually cure tinnitus?

 

[JohnAdams]

Out of Frequency Therapeutics, Decibel Therapeutics, Sensorion and Otonomy which one do you believe will actually cure tinnitus?

Cure is a strong word. I think enough has been discovered already about healing the ear that they probably all have something going on that will be effective to restore hearing, and at the very least reduce tinnitus.

 

[Lucifer]

Cure is a strong word. I think enough has been discovered already about healing the ear that they probably all have something going on that will be effective to restore hearing, and at the very least reduce tinnitus.

I do believe that hearing regeneration is our best bet in terms of a cure for tinnitus or an improvement. I also believe this can help with hyperacusis as well.

 

[urgentresearch]

COMING THIS FALL
Les Study Results de FX-322
Starring Susan King ft. Will McLean
September 18, 2019

https://plan.core-apps.com/aao2019/event/d29afee0ef623a96e8827526a952c271​

 

[Lucifer]

COMING THIS FALL
Les Study Results de FX-322
Starring Susan King ft. Will McLean
September 18, 2019

https://plan.core-apps.com/aao2019/event/d29afee0ef623a96e8827526a952c271​

How do you know when they are going to release the results? It doesn't state a date on their website other than later in 2019.

 

[urgentresearch]

How do you know when they are going to release the results? It doesn't state a date on their website other than later in 2019.

We will at least get the new study results abstract on September 18. (Possibly sooner, if the conference organizer decides to make the abstracts public before the conference itself begins... which isn't too uncommon.)

As for the full text, the paper, that will depend on the embargo date and publishing schedule.

But we should get more info on results. I'm basing this on the content of Frequency's press release from last month:

"Frequency plans to present the Phase 1/2 results at a major otolaryngology meeting in 2019 and to submit the results for publication."

This September 18 meeting is the meeting referenced, unless I am totally misreading something.