Lenire — Bimodal Stimulation Treatment by Neuromod

[kelpiemsp]

They kind of are if you consider Hubert Lim jumping ship. He will take his expertise from Susan Shore with him.

That being said I'm not sure how I feel about Susan Shore continuing as though Neuromod doesn't even exist. I guess she (or Minnesota) may come up with approaches that are better than Neuromod, but if you're talking about total number of participants, Lenire is poised to dwarf the other two, which means they should be able to gather orders of magnitude more data and hopefully learn a lot more from that.

It could very well be that the anatomical point of stimulation does matter but after reading through these threads I see no data to indicate any clear advantages of one vs. another. If there are it will be deduced by trial and error.

Why would Hubert Lim take Susan Shore's expertise? They are from separate, non collaborating institutions. Of course you can see no data comparing the different areas of stimulation, it's not available.

I can think of several reasons why Lenire won't be a hit in the US vs. Susan Shore or the University of Minnesota. For example, Americans would rather use an integrated wearable, only in your ear vs. an iPod, headphones, and a tongue stick.

 

[Heinrich_S7]

Why would Hubert Lim take Susan Shore's expertise? They are from separate, non collaborating institutions. Of course you can see no data comparing the different areas of stimulation, it's not available.

I can think of several reasons why Lenire won't be a hit in the US vs. Susan Shore or the University of Minnesota. For example, Americans would rather use an integrated wearable, only in your ear vs. an iPod, headphones, and a tongue stick.

Lenire is going to be the only option for Americans though for a while.

Hopefully University of Michigan and University of Minnesota release soon.

 

[GlennS]

Why would Hubert Lim take Susan Shore's expertise?

I was always under the impression the two worked together.

 

[Jack Straw]

So if my THI is 58 and if I get 7 to 10 points reduction on the THI [at best] from Lenire, I'm looking at 48 which is a moderate handicap?

I'm beginning to wonder if it's worth it.

Am I getting this right?

The average was 20 point reduction.

 

[jmasterj]

I was always under the impression the two worked together.

I don't think they worked together. If I remember correctly Hubert Lim posted research and did the first studies with mice and Susan Shore maybe based some of her work on Hubert Lim's findings.

 

[spedgas]

I was always under the impression the two worked together.

Hubert Lim got his Master's and PhD from the University of Michigan. They aren't working together though.

 

[jay777]

I can think of several reasons why Lenire won't be a hit in the US vs. Susan Shore or the University of Minnesota. For example, Americans would rather use an integrated wearable, only in your ear vs. an iPod, headphones, and a tongue stick.

If Lenire is a flop in the US, could Susan Shore or the University of Minnesota even bring their product to market from an investment point of view?

 

[Heinrich_S7]

If Lenire is a flop in the US, could Susan Shore or the University of Minnesota even bring their product to market from an investment point of view?

If the Lenire works I highly doubt it will be a flop anywhere. Tons of medications cause side effects but people put up with them because it helps the symptoms of their problem.

Having a little tab in my mouth for 30-60 minutes is nothing.

If Lenire does work too, I expect it to make headlines. Dozens of millions in the US have tinnitus and those people need treatment. This could very well be the beginning of our version of insulin.

 

[Jack Straw]

New Theory:

I think @Paulmanlike sending his knickers to Ross may be what is slowing the whole release process down.

 

[Watasha]

They kind of are if you consider Hubert Lim jumping ship. He will take his expertise from Susan Shore with him.

That being said I'm not sure how I feel about Susan Shore continuing as though Neuromod doesn't even exist. I guess she (or Minnesota) may come up with approaches that are better than Neuromod, but if you're talking about total number of participants, Lenire is poised to dwarf the other two, which means they should be able to gather orders of magnitude more data and hopefully learn a lot more from that.

It could very well be that the anatomical point of stimulation does matter but after reading through these threads I see no data to indicate any clear advantages of one vs. another. If there are it will be deduced by trial and error.

If one believes in the potential for Neuromod to further optimize its treatment, there is nothing to be concerned about Michigan or Minnesota continuing their trials and in fact, I like the competition.

 

[dayma]

If one believes in the potential for Neuromod to further optimize its treatment, there is nothing to be concerned about Michigan or Minnesota continuing their trials and in fact, I like the competition.

I love the competition also. Who knows, Shore may learn from Neuromod and adjust their device and/or timings. The more data points, the better.

 

[GlennS]

Research, yes. Reinventing the wheel, no. They have to do something other than retrace the same exact steps and getting the same exact result over and over. If it becomes just a reinventing the wheel exercise then it would validate the impression I had of Susan Shore being only interested in busywork to justify her tenure. So I hope she has some innovations planned.

 

[Heinrich_S7]

If a more advanced version of this treatment came to fruition, I'm trying to imagine what it would be.

I wonder if just timing alone could drastically increase performance of the treatment.

 

[Watasha]

Research, yes. Reinventing the wheel, no. They have to do something other than retrace the same exact steps and getting the same exact result over and over. If it becomes just a reinventing the wheel exercise then it would validate the impression I had of Susan Shore being only interested in busywork to justify her tenure. So I hope she has some innovations planned.

@GlennS How did you come to this impression of Dr. Shore?

@Hazel Didn't Dr. Shore agree to a podcast with us? Perhaps we can ask her any anticipated differences between her research and Neuromod's?

 

[Hazel]

@Hazel Didn't Dr. Shore agree to a podcast with us? Perhaps we can ask her any anticipated differences between her research and Neuromod's?

Yes she did but she wanted to wait until her trial data is published, so it'll be a while. We'll keep trying though.

 

[GlennS]

How did you come to this impression of Dr. Shore?

Just compare the state of her research to Neuromod over the same timeline. I wouldn't be surprised if she just keeps running tests with 100-200 participants years after Lenire is in wide circulation and already assisting people. I just don't get the sense her research is actually GOING anywhere beyond what could be gleaned from the very first trial. I hope I'm wrong but that's my impression.

 

[Martin69]

My THI score is 68 today (a really loud, bad day).
On low days, like yesterday, THI definitely goes down (maybe around 45-50).
A reduction should be at least 15 points for me. Otherwise, I see no big difference.

 

[Autumnly]

You guys!!!!!!

Neuromod Devices Limited, the Irish medical technology company specialising in non-invasive neuromodulation technologies, is delighted to provide an update on the availability of the Lenire® tinnitus treatment system. The first medical facility (Neuromod Medical) offering treatment with Lenire® is now accepting requests for appointments in Dublin, Ireland at www.neuromodmedical.com. More information about how to request an appointment is provided below.

A tinnitus assessment at Neuromod Medical will cost €250. You should expect to spend at least 45 minutes and up to 90 minutes with the clinicians at Neuromod Medical. The tinnitus assessment appointment will include a detailed medical history collection and a full hearing test, as well as an examination of your ears and measurement of your tinnitus loudness and pitch. In addition, you will be asked to complete questionnaires that the audiologist will use to determine how tinnitus impacts on your daily life. The audiologist will discuss your treatment expectations and suitability for treatment with Lenire®. Lenire® is not suitable for everyone with tinnitus. If the audiologist determines that you are not suitable for treatment with Lenire® and that an alternative treatment is more appropriate, you will be provided with a detailed referral recommendation. If you are suitable for treatment with Lenire®, you will be given an appointment to return a few weeks later for your fitting visit, when you will get the Lenire® device.

A standard course of treatment with Lenire® will cost €2,500 and will include four appointments with Neuromod Medical over the course of three months (including the first assessment visit).

 

[Rohov Dmytro]

IT'S HAPPENING. Got an email to schedule my visit.

 

[Rohov Dmytro]

UPDATED WEBSITE
https://www.lenire.ie/

 

[dayma]

Got the email also. Looks like it's not going to be do'able for foreigners unless you want to fly to Ireland 4 times and/or stay there. Welp.

 

[EDDTEKK]

Where are the boobs @annV?

 

[GlennS]

A standard course of treatment with Lenire® will cost €2,500 and will include four appointments with Neuromod Medical over the course of three months (including the first assessment visit).

More than one reason to celebrate

The Promise(tm) from AnnV: I will post my boobs here if the device costs less than €3000 EUR.

 

[Ruse]

Happy that they priced this at €2500 instead of €4000!

Good to hear they are collecting data as well.

 

[COYS]

Not as expensive as I was expecting.

 

[TibuJenkins]

Godspeed to those that can get to the Ireland offices. I wish you all the very best.

 

[Soren]

Hopefully clinics in Germany will follow soon after.

 

[Skinjob]

Got the email also. Looks like it's not going to be do'able for foreigners unless you want to fly to Ireland 4 times and/or stay there. Welp.

If you use Airbnb, you can book a cheap room in Dublin for about $1,000 per month. That is my current intention. I've already talked to my boss about a six-week medical leave.

 

[Krolo]

Alright. Now I need to find me an Irish person I can stay with for all these months. If I am eligible for the treatment, that is.

 

[Markku]

It clearly states:

"A standard course of treatment with Lenire® will cost €2,500 and will include four appointments with Neuromod Medical over the course of three months (including the first assessment visit)."

Keyword including. So the €2,500 appears to be the total price.