My Posting Place

mfw my tinnitus is not easy to mask

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I wish... I've had T for 6+ months and it's really not getting any easier.
Back towards the beginning there were some days that it was a lower-pitched static instead of this clusterfuck of shrill screechy thingies. That sucked too of course, but it was definitely was waaaay easier to deal with than the mind-warping screeeeeeching!!
Different types of tinnitus are totally different animals. I must say, if God exists I think he deserves a medal for being so brilliantly sadistic.

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here ya go:

https://www.frontiersin.org/articles/10.3389/fncel.2018.00120/full

"Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells"

it is an on and of switch. the ability is there. that's what fx-322 is all about.

However, maybe there's an easier way.


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417821/

"Overexpression of β-catenin caused an increase in hair cell marker-positive cells"


https://www.ncbi.nlm.nih.gov/pubmed/24328990

"Common food additive carrageenan stimulates Wnt/ β-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction."


https://en.wikipedia.org/wiki/Carrageenan

it's in edible red seaweed.

"Carrageenan has been studied in laboratory animals for its potential effects on intestinal and immune functions following oral intake or gavage, with no effects on organ pathology, clinical chemistry, hematology, or normal health.[26] Dietary carrageenan had no carcinogenic, genotoxic, developmental, or reproductive effects in laboratory animals, and was found to be safe in one study on human infants.[26] "

but then there's this.

https://wellnessmama.com/2925/what-is-carrageenan/

"Although derived from a natural source, it appears to be particularly destructive to the digestive system, triggering an immune response similar to that your body has when invaded by pathogens like Salmonella. The result: "It predictably causes inflammation, which can lead to ulcerations and bleeding"

So, here's this.

https://www.modernistpantry.com/car...MI7frz3JvA3AIVE4nICh18xw3uEAkYASABEgIZxPD_BwE

I (out of desperation) wonder if eating lot's of this stuff could trigger spontaneous regeneration of hair cells. Or give us cancer. But then the question becomes, what's worse? Dying of cancer or living with tinnitus?

once again:
"Common food additive carrageenan stimulates Wnt/ β-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction." "Overexpression of β-catenin caused an increase in hair cell marker-positive cells".

The eustachian tubes connect to the inner ear so maybe snort it? I'm no doctor.

Food for thought. This seems to me to be as plausible as adipose stem cell injections. Definitely better that that nasty Apple Cider Vinegar or the over the counter pills that don't so jack squat.
 
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Visual snow keep getting worse...Tinnitus the gift thats keep giving
I've noticed. Mine comes and goes in waves. I've been doing research on the relationship between the two, and I thing neuroactivity in the DCN/IC is contributing to hyperactivity in the Fusiform Gyrus.
 
I've noticed. Mine comes and goes in waves. I've been doing research on the relationship between the two, and I thing neuroactivity in the DCN/IC is contributing to hyperactivity in the Fusiform Gyrus.

Since childhood, always had floater and visual snow but since T onset it seem to get worse.
 
here ya go:

https://www.frontiersin.org/articles/10.3389/fncel.2018.00120/full

"Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells"

it is an on and of switch. the ability is there. that's what fx-322 is all about.

However, maybe there's an easier way.


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417821/

"Overexpression of β-catenin caused an increase in hair cell marker-positive cells"


https://www.ncbi.nlm.nih.gov/pubmed/24328990

"Common food additive carrageenan stimulates Wnt/ β-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction."


https://en.wikipedia.org/wiki/Carrageenan

it's in edible red seaweed.

"Carrageenan has been studied in laboratory animals for its potential effects on intestinal and immune functions following oral intake or gavage, with no effects on organ pathology, clinical chemistry, hematology, or normal health.[26] Dietary carrageenan had no carcinogenic, genotoxic, developmental, or reproductive effects in laboratory animals, and was found to be safe in one study on human infants.[26] "

but then there's this.

https://wellnessmama.com/2925/what-is-carrageenan/

"Although derived from a natural source, it appears to be particularly destructive to the digestive system, triggering an immune response similar to that your body has when invaded by pathogens like Salmonella. The result: "It predictably causes inflammation, which can lead to ulcerations and bleeding"

So, here's this.

https://www.modernistpantry.com/car...MI7frz3JvA3AIVE4nICh18xw3uEAkYASABEgIZxPD_BwE

I (out of desperation) wonder if eating lot's of this stuff could trigger spontaneous regeneration of hair cells. Or give us cancer. But then the question becomes, what's worse? Dying of cancer or living with tinnitus?

once again:
"Common food additive carrageenan stimulates Wnt/ β-catenin signaling in colonic epithelium by inhibition of nucleoredoxin reduction." "Overexpression of β-catenin caused an increase in hair cell marker-positive cells".

The eustachian tubes connect to the inner ear so maybe snort it? I'm no doctor.

Food for thought. This seems to me to be as plausible as adipose stem cell injections. Definitely better that that nasty Apple Cider Vinegar or the over the counter pills that don't so jack squat.

I will take the time to read this and all your future post, right now I am bombared with task
if we really can make a "Do it yourself FX-322" that would be top meme status
 
so @JohnAdams so you had been lurking MPP for several months I heard?
No just like 1 and a half months.
Also, Im now unsure about my research refarding carrageenan. The chemical plays an imporatant role inside the cell but is also produced inside the cell. I do not believe ingesting it in large quantities would affect the way it functions inside the cell. The primary way that is accomplished is through a process called Wnt (wint) pathway signalling and some other stuff that not only activates the dormant progenitor cells but then also differentiates them into hair cells. It is probably far more complicated than just eating some food or some chemical.
 
I just had a horrible thought. What if FX 322 works perfectly and the investors get super super greedy because this will be a brand new technology and they can confuse people with technical jargon and make it cost like $20,000 per ear?
 
I just had a horrible thought. What if FX 322 works perfectly and the investors get super super greedy because this will be a brand new technology and they can confuse people with technical jargon and make it cost like $20,000 per ear?
I disagree...anything that includes "FX322 works perfectly" is a splendid thought, not a horrible one. I'd gladly sell the clothes off my back and go homeless and take out loans before you could say "cochlea".
 
um guys lets talk about this in a private PM, i realized that it's not a good idea to speculate & make memes about bio tech, researchers, or scientist. This stuff actually can show up in Google search results and do damage to the reputation of researchers trying to help us. it's already too late tbh and I'm sure with MPPs 67,000 views actual researchers had to of came here at least once and probably view us as pathetic mentally ill people that we are.
 
I understand why people may have contempt for God or the notion of God, the creator, that's actually part of Hindusim and Gnosticism, that the creator messed up when He made the world. But this is a support forum for people sharing in a disease. Some of us may be Christians, Muslims, Jews, whatever. I think it would be better to not denigrate people's beliefs.
I don't know about the rest of the site, but it's just kind of convention that most people on MPP are either atheist or agnostic. Sort of like how you would probably see atheism get flack on a Christian forum.
 
I don't know about the rest of the site, but it's just kind of convention that most people on MPP are either atheist or agnostic. Sort of like how you would probably see atheism get flack on a Christian forum.

Oh okay. Well just for the record Im disavowing any connection to MPP because I dont want to be associated with people that denigrate other people's spiritual beliefs, especially on a website that is supposed to be a support network for suffering people. I love all of my fellow human beings regardless of their beliefs, sexual orientation etc. They only people I would denigrate would be people that purposefully inflict pain and suffering on other people, especially children.
 
Oh okay. Well just for the record Im disavowing any connection to MPP because I dont want to be associated with people that denigrate other people's spiritual beliefs, especially on a website that is supposed to be a support network for suffering people. I love all of my fellow human beings regardless of their beliefs, sexual orientation etc. They only people I would denigrate would be people that purposefully inflict pain and suffering on other people, especially children.
We don't. The most militant atheist here (Jazzer) left the post a while ago. He's just active on here very rarely. Most of us really aren't and any reference to religion happens once in a blue moon. I don't think JCB is an atheist, so she probably posted that gif ironically.

Other than that I'd say the only other guys I know for a fact are atheists are me and contrast, and we don't really ever mention it.
 
I understand why people may have contempt for God or the notion of God, the creator, that's actually part of Hindusim and Gnosticism, that the creator messed up when He made the world. But this is a support forum for people sharing in a disease. Some of us may be Christians, Muslims, Jews, whatever. I think it would be better to not denigrate people's beliefs.

Maybe you are right JA - perhaps it's too sensitive a subject to bring up.
Personally I feel that we should all respect the right of others to believe what they wish.
 
We don't. The most militant atheist here (Jazzer) left the post a while ago. He's just active on here very rarely. Most of us really aren't and any reference to religion happens once in a blue moon. I don't think JCB is an atheist, so she probably posted that gif ironically.

Other than that I'd say the only other guys I know for a fact are atheists are me and contrast, and we don't really ever mention it.

Slight correction TFF - I regard myself an agnostic.
There is no way I can 'know' of the existence, or otherwise, of god - nobody can 'know' that.
People can believe in faith - but that does not make god's existence an objective reality.
 

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