Retigabine (Trobalt, Potiga) — General Discussion

[RaZaH]

Please keep in mind that I just started . I also had a bad day today , maybe I need to increase the dosage already.
There is no such thing as a miracle drug in my opinion. I seem to be the only one with such a reaction to this drug butI am very sensitive to all drugs.I am reporting to the best of my abilities as I go along this path. Also , I am sure someone will imagine that I am just sitting here in silence but its far from that simple, I do get relief but it is temporary. It might even be worse inbetween dosages or just perception when it returns ?
It might all change tomorrow.

 

[Christian78]

@Christian78
"ok effect "
I get almost complete silence on 1x100mg , did you ever get complete silence or near that on your travels through Trobalt land ?

never, i t happen few times on 200 and than effect washed away after continuous use of trobalt

 

[Christian78]

wow, trobalt sounds like a miracle drug

+ it's working on tinnitus which is OVER 2 years old.

are there any other similar cases?

note: 100mg is low dose. maybe a higher dose would make effect last longer/even permanent?

there is no permanent effect, we tried all and mpt had permanent for now effect, and we cant make conclusion based on one person if 12 of us dont get permanent effect.
he may be lucky or he lover his t, so t passed away naturaly.

 

[Rog]

Does anyone know if Reigabine is available in Colombia?? Couldn't find an answer in the web.
Thank you

 

[xanaxvictim]

Attention! Someone on a Benzo withdrawal support site experimenting with Potiga also independently reported significant improvement of her benzo-induced T with it. She only takes Potiga 2 times a week

"Actually, very well. I only take 600mg twice a week. My T is better than ever. The side effects scare me so I am taking it easy. I did a titration experiment with potiga and crushed the pill and put it into water. I drank to simulate a taper dose,,,,,,,, HOLY SMOKES, it hit me like 4 Xanax!! Then I read the bottle DO NOT CRUSH PILLS! I guess they are time release without saying "XR".
It's a anti seizure drug so it's no wonder it behaves like a tranquillizer.

From what I have read online some think pushing the potassium channel can send the DNC back into healing mode repairing a chemical imbalance. Like taping on a loose nail to drive it back in to the right spot (I think that is what the headache means but I really do not know)

Also read you can't mix potiga with gabapentin or Valproic acid!!! So I quit gabapentin too.

Ears are the best ever with the 2 times a week potiga treatments. I know its working since the potiga gives me a headache and during the potiga headaches the T is very low. I stopped for a week and the T is still lower than before. So far it's working for me.

I REALLY suspect that potiga must be addictive so I take it only twice a week and then once a month washout for 7 days. When I took the crushed powder I knew it was an abuse-able drug!!

Potiga ultimately manipulates calcium via the K channel but in a different way than a benzo manipulates calcium. Let's call it OPPOSITE of a benzo, kind of."

 

[SoulStation]

Attention! Someone on a Benzo withdrawal support site experimenting with Potiga also independently reported significant improvement of her benzo-induced T with it. She only takes Potiga 2 times a week

"Actually, very well. I only take 600mg twice a week. My T is better than ever. The side effects scare me so I am taking it easy. I did a titration experiment with potiga and crushed the pill and put it into water. I drank to simulate a taper dose,,,,,,,, HOLY SMOKES, it hit me like 4 Xanax!! Then I read the bottle DO NOT CRUSH PILLS! I guess they are time release without saying "XR".
It's a anti seizure drug so it's no wonder it behaves like a tranquillizer.

From what I have read online some think pushing the potassium channel can send the DNC back into healing mode repairing a chemical imbalance. Like taping on a loose nail to drive it back in to the right spot (I think that is what the headache means but I really do not know)

Also read you can't mix potiga with gabapentin or Valproic acid!!! So I quit gabapentin too.

Ears are the best ever with the 2 times a week potiga treatments. I know its working since the potiga gives me a headache and during the potiga headaches the T is very low. I stopped for a week and the T is still lower than before. So far it's working for me.

I REALLY suspect that potiga must be addictive so I take it only twice a week and then once a month washout for 7 days. When I took the crushed powder I knew it was an abuse-able drug!!

Potiga ultimately manipulates calcium via the K channel but in a different way than a benzo manipulates calcium. Let's call it OPPOSITE of a benzo, kind of."

I don't know if she has a grasp on the MOA but whatever if it works for her that's great. Ask her to sign up for tinnitus talk

 

[Danny Boy]

Bad news guys/gals....The effect of trobalt on 200mg seems to be less effective than it was on 100mg and since I ran out of the 100mg tablets...Yeah, I'm in a bad place again!

 

[dan]

Bad news guys/gals....The effect of trobalt on 200mg seems to be less effective than it was on 100mg and since I ran out of the 100mg tablets...Yeah, I'm in a bad place again!

Cut the 200mg pill in half.

 

[Danny Boy]

Cut the 200mg pill in half.

Might have to try that...But why on earth was 100mg more effective than 200mg? Seriously, it's going back to baseline on 200mg!?

 

[Telis]

Might have to try that...But why on earth was 100mg more effective than 200mg? Seriously, it's going back to baseline on 200mg!?

Placebo to start

 

[Danny Boy]

Placebo to start

I wouldn't have said placebo, as I did check the volume by plugging my ears. Still, this stuff does help with my sensitivity, so it must be doing something.

 

[SoulStation]

@Danny Boy you're probably over monitoring. I'm trying to give that up and feel like I'm doing better now that I'm not checking my t as obsessively.

 

[dan]

I wouldn't have said placebo, as I did check the volume by plugging my ears. Still, this stuff does help with my sensitivity, so it must be doing something.

Danny tell me, before starting Trobalt, did you have to plug your ears to hear your tinnitus?

 

[Danny Boy]

@Danny Boy you're probably over monitoring. I'm trying to give that up and feel like I'm doing better now that I'm not checking my t as obsessively.

Guess your right, maybe, 300mgx3 a day will be better?

 

[Danny Boy]

Danny tell me, before starting Trobalt, did you have to plug your ears to hear your tinnitus?

No, mine is heard over everything.

 

[dan]

No, mine is heard over everything.

Right. So hearing it over everything and then not hearing it, cannot be placebo.
Still, if you have to plug your ears to hear it now, then its still within mild range, don't panic.

 

[Danny Boy]

Right. So hearing it over everything and then not hearing it, cannot be placebo.
Still, if you have to plug your ears to hear it now, then its still within mild range, don't panic.

No, no...It's starting to go back to baseline, just slowly.

 

[SoulStation]

Guess your right, maybe, 300mgx3 a day will be better?

I don't know I'm sure you'll get high on 300 mg. . Just accepting that it's there and trying to move on maybe. But that's for another thread.

 

[Danny Boy]

I don't know I'm sure you'll get high on 300 mg. . Just accepting that it's there and trying to move on maybe. But that's for another thread.

I have tried a 300mg tablet and didn't feel high at all.

 

[SoulStation]

I have tried a 300mg tablet and didn't feel high at all.

Great then go for it. I mean whatever gets you through the night.

 

[dan]

No, no...It's starting to go back to baseline, just slowly.

I wouldn't go up. I'd stay at 100mg - if its not broke dont fix it.

 

[xanaxvictim]

I don't know if she has a grasp on the MOA but whatever if it works for her that's great. Ask her to sign up for tinnitus talk

Benzo induced T+H probably because Benzo (more specifically Benzo tolerance/withdrawal) caused a down regulation of GABAA receptors and the subsequent GABA/Glutamate inhibitory/excitation imbalance, along the central auditory pathway. This is also the same proposed mechanism for noise induced T and AM-101 is specifically designed to target NMDA receptor after noise exposure. However in my opinion the GABA/Glutamate imbalance is only part of the story, the imbalance somehow resulted in potassium channel anomaly and sustained T. Just a speculation but it seems that I have seen someone also reported Xanax induced T being annihilated by Trobalt on this site.

 

[Telis]

Benzo induced T+H probably because Benzo (more specifically Benzo tolerance/withdrawal) caused a down regulation of GABAA receptors and the subsequent GABA/Glutamate inhibitory/excitation imbalance, along the central auditory pathway. This is also the same proposed mechanism for noise induced T and AM-101 is specifically designed to target NMDA receptor after noise exposure. However in my opinion the GABA/Glutamate imbalance is only part of the story, the imbalance somehow resulted in potassium channel anomaly and sustained T. Just a speculation but it seems that I have seen someone also reported Xanax induced T being annihilated by Trobalt on this site.

Who was that?

 

[xanaxvictim]

Who was that?

https://www.tinnitustalk.com/threads/retigabine-trobalt-potiga-—-user-experiences.6047/page-2
johno claims his central T induced by Xanax was cured

 

[Telis]

https://www.tinnitustalk.com/threads/retigabine-trobalt-potiga-—-user-experiences.6047/page-2
johno claims his central T induced by Xanax was cured

Not sure if that would be considered "annihilated his T" but ok. My T moves around and certain sounds disappear but my T is far from being annihilated.

 

[OddV]

What about us poor *** that got this crap from ear infections @xanaxvictim, is there nothing for us? I don't think we know yet on this drug or others.

 

[SoulStation]

https://www.tinnitustalk.com/threads/retigabine-trobalt-potiga-—-user-experiences.6047/page-2
johno claims his central T induced by Xanax was cured

He speculates. that doesn't sound sure to me . Why don't you try it and see for yourself? Then you'll know.

 

[SoulStation]

Also read past posts by @benryu .... He has said the same thing as what you're suggesting from what I remember. I think there is some sort of missing link between the glutamate excess and K channel dysfunction though.

 

[xanaxvictim]

He speculates. that doesn't sound sure to me . Why don't you try it and see for yourself? Then you'll know.

Of course I can't be sure unless I experiment with it myself, but I suppose it's a very dangerous drug which Drs don't normally prescribe to T sufferers. @Mpt got it from a relative who's also a Dr.
Just want to be more cautious, I got this crap with prescribed CNS medication.

 

[RaZaH]

My T was caused by Benzo withdrawal. Retagabine seems highly effective for me , especially in the first few days.
Was not so effective yesterday for some reason.