With all due respect... As I have been more or less stating for a while now, I personally believe you have too many variables/meds/factors stirring around in the pot to make any blanket statements about what is and what is not being caused by Retigabine. There are too many interactive potentials, and not nearly enough "stability" of sequence" in what I am at least reading into your posts.
Indeed we are not pretending this Retigabine evaluation here at TT is a "trial" in much other than attempt and hopes of some insights and directions. Remember, there is a complete lack of screening requirements (you just have to get hold of the stuff!), there is huge variability in starting points for each trialee, and there's the multi-mixture of "other" things people are taking along with it. Let's not even get into individual dosing regimens! (The aspirin approach, all the way to the fixed "1200 mg/day effective dose requirement"). Etc., etc.
So to sum up...The less "other" meds, supplements, lifestyle changes, misc. stuff, etc. introduced along the way, the better in terms of evaluation. If the only "control" we have in each case is "ourselves", then it is just basic common sense that the more we "control" the "control" and keep stuff as clean and clear as possible, the more of an objectively subjective assessment we can make of the Retigabine variable itself!
My two cents... Best, Zimichael