MemberWell, it works in the same way keppra does but is 10x more potent. It functions the same.
Brivaracetam — KV3.1 Modulator
- Thread starter Danny Boy
- Start date
Well, it works in the same way keppra does but is 10x more potent. It functions the same.
Np then, if you are sure that it is kv3.1 modulator. Im not qualified to conclude anything to a way or to another.
Well, we will know when it comes out...Which is hopefully soon. We need a KV3.1 drug as soon as possible.
Even if Brivarectam doesn't work on Kv3.1 channels there is always Autifony and I'm pretty sure that more Kv3.1 modulators are comming. If not for tinnitus then for epilepsy. It's just a matter of time now...
Well, keppra works on the KV3.1 channels so I would guess this is too. I mean, they basically work in the same way, just that this is more potent.
I hope so. But when listing something as "more potent" doesn't necessarly mean it works the same way. The result in terms of siezures in epilepsy patients might be that you need less Brivarectam then Keppra but they don't have to have the same mechanism of action.
I looked it up online and it said the mechanism is basically the same. So, I'd say it does. Anyway, it's worth a try...Here I come Spain.
Hey dannyboy
I was just reading about this new drug online and that it's gone for approval since January so could be out soon everything going well.
I couldn't find anything online about them testing it for tinnitus just for epilepsy. Is it being marketed as an epilepsy drug with potential to treat tinnitus or whats their plans do you know?
Thanks
I was just reading about this new drug online and that it's gone for approval since January so could be out soon everything going well.
I couldn't find anything online about them testing it for tinnitus just for epilepsy. Is it being marketed as an epilepsy drug with potential to treat tinnitus or whats their plans do you know?
Thanks
no plans in regards to Tinnitus ... the tinnitus aspect is just something that emerged here on the forums.
It seems that this Bivaracetam will be sold under a product named "Briviact".
I guess what's left is the Marketing Authorization itself (for UE availability).
Not so much happened since January though
"On 19 November 2015, the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Briviact, intended for the treatment of partial-onset seizures. The applicant for this medicinal product is UCB Pharma SA."
http://www.ema.europa.eu/ema/index..../human_smop_000901.jsp&mid=WC0b01ac058001d127
http://www.ucb.com/investors/UCB-tomorrow/brivaracetam
I guess what's left is the Marketing Authorization itself (for UE availability).
Not so much happened since January though
"On 19 November 2015, the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Briviact, intended for the treatment of partial-onset seizures. The applicant for this medicinal product is UCB Pharma SA."
http://www.ema.europa.eu/ema/index..../human_smop_000901.jsp&mid=WC0b01ac058001d127
http://www.ucb.com/investors/UCB-tomorrow/brivaracetam
Great news !It seems that this Bivaracetam will be sold under a product named "Briviact".
I guess what's left is the Marketing Authorization itself (for UE availability).
Not so much happened since January though
"On 19 November 2015, the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Briviact, intended for the treatment of partial-onset seizures. The applicant for this medicinal product is UCB Pharma SA."
http://www.ema.europa.eu/ema/index..../human_smop_000901.jsp&mid=WC0b01ac058001d127
http://www.ucb.com/investors/UCB-tomorrow/brivaracetam
.. this will be out in a few months i guess now it has been approved ... good news
Great news !
Spain it is.
anyone have an idea if Portugal is also a place to buy these meds without prescription. i`ll be in portugal in a few weeks ...
Interesting thread. I don't know much about the different drugs that are available for tinnitus. Is this a significant development? @Danny Boy
This is not a drug intended for tinnitus. This one is close to Keppra which didn't helped Tinnitus sufferers but helped hyperacusis.
The interesting point is that it is more potent than Keppra and has way less secondary effects than trobalt.
So I would say it's worth a shot.
- Aug 21, 2014
- 5,049
- Tinnitus Since
- 1999
- Cause of Tinnitus
- karma
I love that we have an 8 page thread in the "treatments" forum about a drug which doesn't even exist yet, which has a mechanism of action which has literally zero evidence to suggest that it is useful or safe for any kind of hearing disorder....
We need to stop saying that keppra "helps" people with hyperacusis. There is no reason to believe this is true, any more than that colloidal silver, reiki crystals or any other bullshit anecdote is true.
We need to stop saying that keppra "helps" people with hyperacusis. There is no reason to believe this is true, any more than that colloidal silver, reiki crystals or any other bullshit anecdote is true.
Didn't it actually helped some people over there ? https://www.tinnitustalk.com/threads/levetiracetam-keppra-worked-for-my-hyperacusis.8946/
- Aug 21, 2014
- 5,049
- Tinnitus Since
- 1999
- Cause of Tinnitus
- karma
We have no way of knowing, because uncontrolled anecdotal stories from the internet are not usable data.
Name any given drug, and I can go and find you an account of someone saying it helped their tinnitus, and someone claiming that it caused it. Humans are very, very bad at understanding causality as it relates to their personal, subjective experience... If not, we wouldn't need controlled studies at all.
I had H for well over a year, and after two rounds of Keppra, it's gone (increased dosage in rnd 2). Coincidence? Perhaps? However, I noticed the difference pretty quickly after starting it, and it hasn't returned since getting off it, so I'm satisfied it worked. Call it anecdotal, but I no longer have H, and it's awesome.
I will add that I don't know if Keppra is the answer for all. For example, aspirin and ibuprofen don't help me if I have a headache (only Excedrin works), but for millions of people they do.
I will add that I don't know if Keppra is the answer for all. For example, aspirin and ibuprofen don't help me if I have a headache (only Excedrin works), but for millions of people they do.
Christian78
Member
- Dec 17, 2013
- 965
- Tinnitus Since
- (Sep 2013)
- Cause of Tinnitus
- progressive tinnitus, time of expiring in next 3-6 months
How long have you been taking keppra to notice that H is gone? and on what minimal dosage?
please tell me
Christian78
Member
- Dec 17, 2013
- 965
- Tinnitus Since
- (Sep 2013)
- Cause of Tinnitus
- progressive tinnitus, time of expiring in next 3-6 months
This is supposed to be the last step before they receive the actual marketing authorisation.
This comission gave a positive opinion uppon drug commercialization. So basically nothing should prevent this drug from reaching the market.
This comission gave a positive opinion uppon drug commercialization. So basically nothing should prevent this drug from reaching the market.
Okay so Market Authorisation should be within the next month at least? My question, if money were no object what is the earliest one could get access to this drug?
- Aug 21, 2014
- 5,049
- Tinnitus Since
- 1999
- Cause of Tinnitus
- karma
Years, probably.
Again. There's no reason to think this drug will help tinnitus. This is an analog of other drugs which already exist and are not known to help tinnitus.
- Aug 21, 2014
- 5,049
- Tinnitus Since
- 1999
- Cause of Tinnitus
- karma
I have a bias against snake oil and fake science. The second someone comes up with a real drug treatment, I'll try it and probably buy stock in the company.
That said, all of these drugs can be very dangerous, and thinking that a keppra analog had action against tinnitus because one person kinda sorta maybe thought that keppra might have helped their hyperacusis is pretty far out there. By all means, eat all the offlabel seizure drugs you want to...
It's ridiculous to me that this thread is in the "treatments" forum, when there is a complete lack of any research in that direction...
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