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Some news from Minbo Shim http://cmclinics.com/

http://www.bionure.com/news/bionure-initiates-a-phase-1-clinical-trial-of-its-lead-compound-bn201-in-the-united-kingdom About BN201 and BN119 Bionure’s compounds BN201 and BN119 are two SGK agonists with remyelinating and neuroprotective activity. Bionure has developed BN201 for the treatment...

http://www.dtu.dk/english/news/2018/01/novo-nordisk-foundation-awards-eur-6-million-to-health-research?id=26f52542-03c7-4eac-8000-cfc36a0b2125

Directly from Dong-Kee Kim Dear Larsen, Thank you for your interest in my paper. I think the delivery of small molecular drugs like steroid or antioxidant, is likely to be commercialized within 10 years. However, it is difficult to predict the timing of delivery of genes or a growth factor...

Nano technology Delivery of small molecular drugs like steroid or antioxidant, is likely to be commercialized within 10 years. However, it is difficult to predict the timing of delivery of genes or a growth factor. It may take decades

http://investors.otonomy.com/phoenix.zhtml?c=234082&p=irol-newsArticle_Print&ID=2325672 Developing OTO-313, an improved formulation of gacyclidine for the treatment of tinnitus. Gacyclidine is a potent and selective N-Methyl-D-Aspartate (NMDA) receptor antagonist, a molecular class with...

http://investors.otonomy.com/phoenix.zhtml?c=234082&p=irol-newsArticle_Print&ID=2325672 OTO-413 is a sustained exposure formulation of BDNF that has been advanced into IND-enabling activities for the treatment of hidden hearing loss. OTO-413 is a proprietary formulation of brain-derived...

https://autifony.com/ Boehringer Ingelheim and Autifony Therapeutics Limited (“Autifony”) today announced that they have signed an agreement about certain aspects of Autifony’s voltage gated potassium channel modulator platform. Boehringer Ingelheim now has an exclusive option to purchase...

Spiral Therapeutics Receives Positive IND Submission Guidance from FDA LPT99 is currently being tested for the treatment of other hearing loss indications, including noise-induced hearing loss and age-related hearing loss. Clinical trials for LPT99 will begin in early 2018...

http://www.isiet2017.org/ This could be interesting :)

Prof. Tzounopoulos, looking for a new employee, perhaps a good sign https://jobs.sciencecareers.org/job/461538/systems-and-behavioral-auditory-neuroscience/

http://www.express.co.uk/life-style/health/847759/ear-tinnitus-treatment-brain-area-symptoms

Yes and when the help came, it was too late for most people

It sounds something that Josef Rauschecker has said (y)

Yes and perhaps AF243 also could help with synapses restoration right?

You just have to eat one "bomb-blast pill" in a few years (y)

Our goal is to begin Phase 2 of FDA clinical trials within the next two years http://houghear.org/in-the-news-state-discovery-could-restore-hearing/

Yes, it's great to hear that the help is on its way, It's just questions about when.

Dr. Cheong the bottom of the site. http://www.fatimah.com.my/HospitalFatimah/orthopaedics_traumatology.html

they have tested it on humans, I do not think it was the big success https://mndrive.umn.edu/brain/clinical-trials-research-opportunities

So right now our best hope is XEN1101/1OP-2198, as a replacement for trobalt? If Phase 2 development beginning by mid-2018.

And it's a good thing his research has been funded by US Department of Defense, US Department of Veteran

Hello Michael, We are not working in those areas but application potential is clearly there. Best, cks Chandan K. Sen, PhD John H and Mildred C. Lumley Chair of Medical Research Professor & Vice-Chairman (Research) of Surgery Associate Dean (Strategic Industry Partnership), College of...

I have sent them an email so we can get an answer to this. If I get an answer, I will come back to you

And researchers already plan to start clinical trials on humans next year :)

I would not care about all side effects, Just that would not have an effect on my eyes

Yes, totally agree, 50,000 is nothing to get you life back I would transfer the money immediately if there was a possibility for a treatment. The best option for a "new trobalt" is 1OP-2198 right ?

Why do you think that? But it would be great if they did.

What does it mean if you do not have any supporting cells left? And who would then benefit from participating in the trial?

I think it's very hard to say, but around 2020 we will have at least 5 companies In the clinic. And then we will know much more. So if everything goes as planned, there could be something on the market in 5 years. If you have enough money to pay for it..

Just they could find another delivery method

So Phase 1 and Phase 2 will be in 2017, and data will come out January 2020. If everything goes well phase 3 will start after 2020 ?

I think we know much more in a couple of years

I hope it will be next year they go to the clinic. Imagine if we could take something orally that could help us.

https://www.ncbi.nlm.nih.gov/pubmed/17260883

Yes, definitely. I hope the side effects not will be Visual Snow and Floaters.

XEN1101: Phase 2 development beginning in mid-2018. Could perhaps help us. Hopefully with fewer side effects

5 - 7 years

http://www.sensorion-pharma.com/en/pipeline/pipeline A phase 2 study is planned for 2018 http://www.sensorion-pharma.com/images/press-release/2017-06-08-PR_SENS-401_phase_1-results_vf_eng.pdf I really like this A 5-HT3 receptor can be administered orally :)

I can not see why you should have broken some rules, it was REALLY interesting and I will try it

There has just been a really interesting post about MDMA, and now it has been deleted :( But I still have a copy :)

OTO-311 is a so-called NMDA receptor antagonist - though differentiated from AM-101 Esketamine is a "non-competitive NMDA antagonist" whereas Gacyclidine is one "Un-competitive blocker NMDA antagonist". They therefore have both the same pharmacological target, but work in a slightly different...

Did anybody try this formula https://www.ncbi.nlm.nih.gov/pubmed/20600769

https://www.technomoves.net/mdma-treat-cancer-illnesses-still-demonised/ Trails to find out could start as soon as May

http://houghear.org/research/ (At the bottom of the text) their aim is to be able to obtain FDA approval within the next 3-5 years Is this a product on the market, Or clinical trial?

You can always come by and pick me up :)

@Samir In Germany :) it sounds good, do you think you must have a German citizenship to participate ?

Regain project https://www.actiononhearingloss.org.uk/community/blogs/our-guest-blog/the-promise-of-new-treatments-for-hearing-loss.aspx

Could it be that this new drug could also help on T. ? http://www.cnbc.com/2017/02/24/new-drugs-may-stop-migraines-before-they-start.html

it sounds crazy

Could this possibly help on T? http://www.cnbc.com/2017/02/24/new-drugs-may-stop-migraines-before-they-start.html

Yes only 17 months, and then trail 1 + 2 + 3. I wish it could go faster

The article says years away, so maybe if we are lucky in 5 years?

Yes you're right (n) But in this one they write of treatment they use has been approved in Germany for over sixty years (Cell therapy FFSC) But I'm not quite sure what it is.

Why is it always in bankok that things happens But I think that there will many more of these places over the next few years

I would love if the first treatment came in Germany :)

https://globenewswire.com/news-release/2017/03/02/930533/0/en/Otonomy-Reports-Fourth-Quarter-and-Full-Year-2016-Financial-Results-and-Provides-Corporate-Update.html Initiation of a Phase 2 clinical trial for OTO-311 for the treatment of tinnitus in the second half of 2017. ?

Has it has not helped you at all with the injection?